CO2Lift V Therapy

CO2Lift V therapy delivers medical-grade carbon dioxide transcutaneously — through the skin — to vulvovaginal tissues. The Bohr Effect, in which elevated CO₂ concentration causes hemoglobin to release bound oxygen, creates a localized hyperoxygenation environment that stimulates tissue repair, improves elasticity, and supports collagen remodeling. Dr. Kevin Stepp, MD, FACOG, URPS offers this treatment in Charlotte, NC as part of his pelvic restoration protocols at Advanced Pelvic Surgery and Urogynecology of Charlotte.

CO2Lift V is a non-hormonal option for addressing Genitourinary Syndrome of Menopause (GSM) and vaginal tissue quality concerns. It does not replace hormone therapy but offers a clinically appropriate alternative for patients who cannot or prefer not to use topical or systemic estrogen. Dr. Kevin Stepp at Advanced Pelvic Surgery and Urogynecology of Charlotte discusses all available options during consultation.

Candidates include women experiencing vaginal dryness, decreased tissue elasticity, mild laxity, or symptomatic GSM. The treatment is also used preoperatively to optimize tissue quality before pelvic surgery, and postoperatively to accelerate healing. Peri- and postmenopausal women benefit most frequently, though premenopausal women with specific tissue concerns are evaluated individually.

A standard protocol at Advanced Pelvic Surgery and Urogynecology of Charlotte involves 3 to 6 treatment sessions spaced 2 to 4 weeks apart, with maintenance sessions every 3 to 6 months. Results are cumulative; most patients report noticeable improvement in tissue tone and comfort after the second or third session. Post-surgical protocols are individualized based on procedure type and healing trajectory.

Most patients describe the sensation as mild pressure and slight warmth. Topical anesthetic is available for sensitive patients. Recovery expectations are reviewed during consultation, and many patients resume normal activities quickly. Active gel contact time is approximately 30 minutes; total appointment time including preparation and post-care review is approximately 45 minutes. In-office sessions are performed at Advanced Pelvic Surgery and Urogynecology of Charlotte, 11210 Golf Links Dr North, #100, Charlotte, NC 28277. To schedule a consultation.

CO2Lift V is one product — the same medical-grade carboxytherapy gel and Bohr Effect mechanism — applied in three different clinical contexts. In-office, Dr. Kevin Stepp applies the gel as part of a supervised visit. As a surgical adjunct, it's integrated into post-operative protocols following labiaplasty, vaginoplasty, or other pelvic procedures. At home, patients use a CO2Lift V kit purchased through our online Wellness Shop to maintain their protocol between visits. The product and mechanism are identical; only the setting and level of clinical oversight differ.

CO2Lift V kits are available for purchase directly through our online Wellness Shop. Dr. Stepp recommends an initial consultation before beginning any at-home carboxytherapy protocol, as CO2Lift V is not appropriate as a substitute for evaluation of undiagnosed pelvic symptoms. For patients already established in care, kits can be securely ordered through our Wellness Shop.