Regenerative Science in Charlotte, NC

PRP, PRFM & PDGF Therapies

Customizing cellular signaling for rapid surgical recovery, tissue scaffolding, and intimate vitality.

The Foundation:
Platelet-Rich Plasma & Fibrin

Regenerative medicine is founded on decades of established surgical science. We utilize your body's own biological mechanisms to support tissue integration and healing.

The Biological Mechanism

Both PRP and PRFM rely on a simple autologous blood draw. When concentrated platelets are applied to tissue, they release a cascade of growth factors that recruit repair cells, stimulate blood vessel formation, and support collagen synthesis.

Customized Processing

We do not use a standard "one-size-fits-all" centrifuge setting. Depending on the surgical goal, we process the plasma into a liquid PRP meant to rapidly dissolve and permeate the tissue, or into a Platelet-Rich Fibrin Matrix (PRFM)—a structural gel designed to "stay put," providing tissue bulk and a sustained release of factors over several days.

Standardized Potency

The Recombinant Alternative: PDGF

While autologous PRP and PRFM are exceptional for scaffolding and volume, their potency naturally varies based on a patient's daily health. When a specific protocol demands strict, highly concentrated consistency, we utilize pure Platelet-Derived Growth Factor (PDGF) through a specialized formulation.

Targeted Clinical Application

At Advanced Pelvic Surgery, we do not rely on a single molecule. Dr. Stepp expertly selects the specific biological tool based on the tissue's exact structural and healing requirements.

Surgical Recovery Support (PDGF)

For complex surgical recovery—such as supporting the incisions of a labiaplasty or vaginoplasty—Dr. Stepp may incorporate recombinant PDGF. Applied to the site, it provides a concentrated signal intended to support healing and modulate inflammation without adding unwanted bulk.

Tissue Scaffolding & Volume (PRFM)

When the goal is structural integrity, hydration, or augmenting the vulvovaginal mucosa, we frequently rely on autologous PRP or PRFM. By utilizing your body's own fibrin matrix, we can physically support the tissue architecture and deliver a slow, continuous wave of rejuvenating growth factors.

Transparency & Regulatory Compliance

At Advanced Pelvic Surgery, we believe in strict clinical honesty. While the broader medical science of PDGF is rooted in advanced wound healing and tissue grafting, the specific recombinant formulation we utilize is listed with the FDA as a cosmetic product designed to improve the appearance of tissue.

Please note: This PDGF formulation is a cosmetic product and is not intended to treat, diagnose, or prevent any disease, or affect the structure or function of the human body. Its application in surgical urogynecology and post-operative healing is considered an off-label or investigational use. Healing-support claims represent our clinical observations and biological rationale, rather than promises based on published gynecologic clinical trials.

Integrative Protocols

Optimizing Biologic Uptake

Whether using PRP, PRFM, or recombinant PDGF, these biologics rely on a vascularized environment to scaffold and repair efficiently.

The CO2Lift V Advantage

To prep the tissue environment and maximize the efficacy of your biologic therapy, Dr. Stepp often recommends CO2Lift V. Utilizing the Bohr Effect, this medical-grade carboxytherapy gel forces a massive influx of oxygen and nutrient-rich blood to the vaginal and vulvar tissues.

By combining localized hyperoxygenation (CO2Lift V) with advanced growth factors (PRP/PDGF), we create a supportive environment for cellular restoration.

Shop CO2Lift V
Advanced Healing Protocols

Integrate Biologic Therapies

Discuss whether customized PRP, PRFM, or recombinant PDGF is the right addition to your surgical recovery or intimate wellness plan.

Schedule a Consultation